Estrogen May Help Men's Hearts

Too much or too little of the hormone, though, can be damaging, study finds

By Serena Gordon
HealthDay Reporter

Related Encyclopedia • AIDS and HIV Infection • Alzheimer's Disease • Amenorrhea • Amniocentesis More... Related Healthscout Videos Baby Steps: Fertility Findings Saving Memories with a Shake: The Alzheimer's Drink Tumor Detecting App: Medicine's Next Big Thing? Powerful Combo Reducing Lymphedema More... Related Animations • Alzheimer's Disease Video Animation • Angioplasty • Breast Reduction • Breast Self-Exam Video More... Related Drug Information • Accupril • Actonel • Altace • Avapro More... Related News Articles • Prostate Size May Be Clue to Severity of Cancer • Many Gay Men Would Support 'Home HIV Test': Study • HIV Severity, Treatment Unrelated to Kids' Mental Woes: Study • Repeat C-Section Best Scheduled at 39 Weeks, Study Says More...

TUESDAY, May 12 (HealthDay News) -- Estrogen has long been implicated as being heart protective in premenopausal women, and a new study suggests that having just the right amount of estrogen might be helpful for men as well.

The study, in the May 13 issue of the Journal of the American Medical Association, found that men with heart failure who had the lowest levels of estrogen had about four times the risk of dying as men with average levels and that men with the highest levels of estrogen had more than twice the risk of dying as men with average levels of the hormone.

Text Continues Below

---

"Among men with chronic heart failure and reduced left-ventricular ejection fraction, high and low concentrations of estradiol [estrogen] compared with the middle quintile of estradiol are related to an increased mortality," the researchers wrote.

However, Dr. Stephen Siegel, a cardiologist at the New York University Langone Medical Center, said that though the study "raises certain issues on how hormones may be affected or may affect cardiac function and mortality, it doesn't necessarily link cause and effect."

Heart failure occurs when the heart muscle weakens and can't pump blood as efficiently to the rest of the body as it should. As many as 5 million people in the United States currently have heart failure, according to the U.S. National Heart, Lung, and Blood Institute. Each year, about 300,000 Americans die as a result of heart failure, the institute reports.

The study, which was done in Poland, included 501 men with an average age of 58 years. All of the men had heart failure and a left ventricular ejection fraction of 28 percent. Ejection fraction is a measure of how well the heart is pumping, and the left ventricle is the heart's main pumping chamber. A normal left ventricular ejection fraction would be between 55 percent and 70 percent, according to the American Heart Association.

Page:  1 | 2 | Next >>