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Page: << Prev | 1 | 2 The researchers found that the course-grit diamond increased the production of compounds associated with wound healing and skin remodeling. These included cytokeratin 16, which helps skin heal after injury.
In addition, the coarse-grit buffing produced antimicrobial peptides that fight infection and substances that break down the skin's structural proteins to let the skin rebuild. The researchers also found that skin produced other substances that induce collagen production.
These changes were not seen in skin treated with the medium-grit device, they noted.
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Their findings are published in the October issue of Archives of Dermatology.
"This research gives us the basis to believe that aggressive microdermabrasion abrasion could potentially result in beneficial effects like we see in other more aggressive procedures, like laser resurfacing," Karimipour said.
However, he predicted that aggressive microdermabrasion would not replace laser resurfacing. Microdermabrasion is not for the most severe cases but rather for fine-line wrinkles and shallow acne scars, he said.
Dr. Jeffrey Salomon, an assistant clinical professor of plastic surgery at Yale University School of Medicine, said that "the more damage induced to the skin, by whatever mechanism, the stronger the body's repair response."
For microdermabrasion-induced injury, coarseness of the grit is only one part of the picture, Salomon said. "The duration of application, pressure applied during the application and the recipient skin thickness are also parameters, just like different grit of sandpaper are used for different types of wood and different types of applications," he said.
Treating the skin first with chemical peeling agents can reduce the amount of grit needed to get a skin-repair response equivalent to that of a coarser-grit wand, Salomon said.
"So there are a variety of parameters that can be manipulated to achieve equivalent results, independent of the coarseness of the grit," he said. "In the end, you do need to induce an injury to the skin to get objective evidence of skin rejuvenation."
More information
The American Society of Plastic Surgeons has more on dermabrasion.
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