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Gene Variants Behind Vulnerability to Yeast Infections
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Page: << Prev | 1 | 2 | 3 This time, the mutation was found in the CARD9 gene, also involved in the immune system.
"Both studies are talking about the same sort of immunological pathways that are triggered in Candida type of infections," Gregg said.
These findings are noteworthy, said Jeffrey Sands, a professor of biological sciences at Lehigh University in Bethlehem, Pa. "We've been co-evolving with fungi for millions of years, and we have these mechanisms for detecting fungal infections, maybe not wiping them out but preventing them from becoming really serious in most cases," Sands said. "The fact that we can now identify individual genes in which there's a mutation, that's certainly a major advance."
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More information
The U.S. Department of Health and Human Services has more on vaginal yeast infections.
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Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 10/28/2009
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SOURCES: Steven Goldstein, M.D., professor, obstetrics and gynecology, New York University Langone Medical Center, New York City; Anthony R. Gregg, M.D., board of directors, American College of Medical Genetics, and director, maternal and fetal medicine, and medical director, genetics, University of South Carolina, Columbia; Bart Jan Kullberg, M.D., professor, medicine, Radboud University Nijmegen, Nijmegen Institute for Infection, Inflammation, and Immunity, and chief, infectious diseases section, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands; Jeffrey Sands, Ph.D., professor and former chair, biological sciences, Lehigh University, Bethlehem, Pa.; Narendra Kumar, Ph.D., assistant professor, pharmaceutical sciences, Texas A&M Health Science Center Irma Lerma Rangel College of Pharmacy, Kingsville; Oct. 29, 2009, New England Journal of Medicine
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