Seroquel

[Quetiapine]

Drug Description
DESCRIPTION

SEROQUEL (quetiapine fumarate) is an antipsychotic drug belonging to a new chemical class, the dibenzothiazepine derivatives. The chemical designation is 2-[ 2-( 4-dibenzo [b, f] [1,4] thiazepin-11-yl-1-piperazinyl) ethoxy]-ethanol fumarate (2: 1) (salt). It is present in tablets as the fumarate salt. All doses and tablet strengths are expressed as milligrams of base, not as fumarate salt. Its molecular formula is C42H50N6O4S2° C4H4O4 and it has a molecular weight of 883.11 (fumarate salt).

Quetiapine fumarate is a white to off-white crystalline powder which is moderately soluble in water. SEROQUEL is supplied for oral administration as 25 mg (peach), 100 mg (yellow) 200 mg (round, white) and 300 mg (capsule-shaped, white) tablets.

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Inactive ingredients are povidone, dibasic dicalcium phosphate dihydrate, microcrystalline cellulose, sodium starch glycolate, lactose monohydrate, magnesium stearate, hydroxypropyl methylcellulose, polyethylene glycol and titanium dioxide.

The 25 mg tablets contain red ferric oxide and yellow ferric oxide and the 100 mg tablets contain only yellow ferric oxide.