Procrit

[Epoetin alfa]

Overdosage & Contraindications
CONTRAINDICATIONS

PROCRIT is contraindicated in patients with: 1) Uncontrolled hypertension. 2) Known hypersensitivity to mammalian cell-derived products. 3) Known hypersensitivity to Albumin (Human).

OVERDOSAGE

Text Continues Below

---

The maximum amount of PROCRIT that can be safely administered in single or multiple doses has not been determined. Doses of up to 1,500 Units/ kg (T. I. W.) for three to four weeks have been administered to adults without any direct toxic effects of PROCRIT itself. Therapy with PROCRIT can result in polycythemia if the hematocrit is not carefully monitored and the dose appropriately adjusted. If the suggested target range is exceeded, PROCRIT may be temporarily withheld until the hematocrit returns to the suggested target range; PROCRIT therapy may then be resumed using a lower dose (see "DOSAGE AND ADMINISTRATION"). If polycythemia is of concern, phlebotomy may be indicated to decrease the hematocrit.