Norvasc

[Amlodipine]

Drug Description
DESCRIPTION

NORVASC® is the besylate salt of amlodipine, a long-acting calcium channel blocker. NORVASC is chemically described as (R. S.) 3-ethyl-5-methyl-2-( 2-aminoethoxymethyl) -4-( 2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate benzenesulphonate. Its empirical formula is C20H25CIN2O5 ° C6H6O3S.

Amlodipine besylate is a white crystalline powder with a molecular weight of 567.1. It is slightly soluble in water and sparingly soluble in ethanol. NORVASC (amlodipine besylate) tablets are formulated as white tablets equivalent to 2.5, 5 and 10 mg of amlodipine for oral administration. In addition to the active ingredient, amlodipine besylate, each tablet contains the following inactive ingredients: microcrystalline cellulose, dibasic calcium phosphate anhydrous, sodium starch glycolate, and magnesium stearate.