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Drug DescriptionSide Effects & Drug InteractionsWarnings & PrecautionsAdditional Info
Clinical PharmacologyOverdosage & ContraindicationsIndications & DosagePatient Info

Imitrex Oral

[Sumatriptan]

Chest Symptoms

Chest discomfort.

Endocrine and Metabolic

Text Continues Below



Dehydration.

Ear, Nose, and Throat

Disorder/ discomfort nasal cavity and sinuses, ear infection, Meniere disease, and throat discomfort.

Eye

Vision alterations.

Gastrointestinal

Abdominal discomfort, colitis, disturbance of liver function tests, flatulence/ eructation, gallstones, intestinal obstruction, pancreatitis, and retching.

Injection Site Reaction

Miscellaneous

Difficulty in walking, hypersensitivity to various agents, jaw discomfort, miscellaneous laboratory abnormalities, "serotonin agonist effect," swelling of the extremities, and swelling of the face.

Mouth and Teeth

Disorder of mouth and tongue (e. g., burning of tongue, numbness of tongue, dry mouth).

Musculoskeletal

Arthritis, backache, intervertebral disc disorder, neck pain/ stiffness, need to flex calf muscles, and various joint disturbances (pain, stiffness, swelling, ache).

Neurological

Bad/ unusual taste, chills, diplegia, disturbance of emotions, sedation, globus hystericus, intoxication, myoclonia, neoplasm of pituitary, relaxation, sensation of lightness, simultaneous hot and cold sensations, stinging sensations, stress, tickling sensations, transient hemiplegia, and yawning. Respiratory: Influenza and diseases of the lower respiratory tract and lower respiratory tract infection.

Skin

Skin eruption, herpes, and peeling of the skin.

Urogenital

Disorder of breasts, endometriosis, and renal calculus.

Postmarketing Experience (Reports for Subcutaneous or Oral Sumatriptan):

The following section enumerates potentially important adverse events that have occurred in clinical practice and that have been reported spontaneously to various surveillance systems. The events enumerated represent reports arising from both domestic and nondomestic use of oral or subcutaneous dosage forms of sumatriptan. The events enumerated include all except those already listed in the ADVERSE REACTIONS section above or those too general to be informative. Because the reports cite events reported spontaneously from worldwide postmarketing experience, frequency of events and the role of sumatriptan in their causation cannot be reliably determined. It is assumed, however, that systemic reactions following sumatriptan use are likely to be similar regardless of route of administration.

Blood

Hemolytic anemia, pancytopenia, thrombocytopenia.

Cardiovascular

Atrial fibrillation, cardiomyopathy, colonic ischemia (see WARNINGS), Prinzmetal variant angina, pulmonary embolism, shock, thrombophlebitis.

Ear, Nose, and Throat

Deafness.

Eye

Ischemic optic neuropathy, retinal artery occlusion, retinal vein thrombosis, oss of vision.

Gastrointestinal

Ischemic colitis with rectal bleeding (see WARNINGS), xerostomia. Hepatic: Elevated liver function tests.

Neurological

Central nervous system vasculitis, cerebrovascular accident, dysphasia, subarachnoid hemorrhage. Non-Site Specific: Angioneurotic edema, cyanosis, death (see WARNINGS), temporal arteritis.

Psychiatry

Panic disorder.

Respiratory

Bronchospasm in patients with and without a history of asthma.

Skin

Exacerbation of sunburn, hypersensitivity reactions (allergic vasculitis, erythema, pruritus, rash, shortness of breath, urticaria; in addition, severe anaphylaxis/ anaphylactoid reactions have been reported [see WARNINGS]), photosensitivity.

Urogenital

Acute renal failure.

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