Diovan

[Valsartan]

Drug Description
DESCRIPTION

Diovan ® (valsartan) is a nonpeptide, orally active, and specific angiotensin II antagonist acting on the AT1 receptor subtype. Valsartan is chemically described as N-(1-oxopentyl)-N-[[2 -(1H-tetrazol-5-yl) [1,1 -biphenyl]-4-yl]methyl]-L-valine. Its empirical formula is C24H29N5O3, its molecular weight is 435.5

Valsartan is a white to practically white fine powder. It is soluble in ethanol and methanol and slightly soluble in water.

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Diovan is available as tablets for oral administration, containing 40 mg, 80 mg, 160 mg or 320 mg of valsartan. The inactive ingredients of the tablets are colloidal silicon dioxide, crospovidone, hydroxypropyl methylcellulose, iron oxides (yellow, black and/or red), magnesium stearate, microcrystalline cellulose, polyethylene glycol 8000, and titanium dioxide.