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Lower Respiratory Tract Infections– caused by -lactamase-producing strains of Haemophilus influenzae and Moraxella (Branhamella) catarrhalis. Otitis Media– caused by -lactamase-producing strains of Haemophilus influenzae and Moraxella (Branhamella) catarrhalis. Sinusitis– caused by -lactamase-producing strains of Haemophilus influenzae and Moraxella (Branhamella) catarrhalis. Text Continues Below
Skin and Skin Structure Infections– caused by -lactamase-producing strains of Staphylococcus aureus, Escherichia coli and Klebsiella spp. Urinary Tract Infections– caused by -lactamase-producing strains of Escherichia coli, Klebsiella spp. and Enterobacter spp.
While Augmentin is indicated only for the conditions listed above, infections caused by ampicillin-susceptible organisms are also amenable to Augmentin treatment due to its amoxicillin content. Therefore, mixed infections caused by ampicillin-susceptible organisms and -lactamase-producing organisms susceptible to Augmentin should not require the addition of another antibiotic. Because amoxicillin has greater in vitro activity against Streptococcus pneumoniae than does ampicillin or penicillin, the majority of S. pneumoniae strains with intermediate susceptibility to ampicillin or penicillin are fully susceptible to amoxicillin and Augmentin. (See Microbiology subsection.) Bacteriological studies, to determine the causative organisms and their susceptibility to Augmentin, should be performed together with any indicated surgical procedures. Therapy may be instituted prior to obtaining the results from bacteriological and susceptibility studies to determine the causative organisms and their susceptibility to Augmentin when there is reason to believe the infection may involve any of the -lactamase-producing organisms listed above. Once the results are known, therapy should be adjusted, if appropriate. Page: << Prev | 1 | 2 | 3 | 4 | 5
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