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If hypoglycemic coma is diagnosed or suspected, the patient should be given a rapid intravenous injection of concentrated (50%) glucose solution. This should be followed by a continuous infusion of a more dilute (10%) glucose solution at a rate that will maintain the blood glucose at a level above 100 mg/ dL. Patients should be closely monitored for a minimum of 24 to 48 hours, since hypoglycemia may recur after apparent clinical recovery. Metformin Hydrochloride Hypoglycemia has not been seen even with ingestion of up to 85 grams of metformin hydrochloride, although lactic acidosis has occurred in such circumstances (see WARNINGS). Text Continues Below
Metformin is dialyzable with a clearance of up to 170 mL/ min under good hemodynamic conditions. Therefore, hemodialysis may be useful for removal of accumulated drug from patients in whom metformin overdosage is suspected. Page: << Prev | 1 | 2 | 3
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