Humalog

[Insulin Lispro]

After abdominal administration, Humalog concentrations are higher than those following deltoid or thigh injections. Also, the duration of action of Humalog is slightly shorter following abdominal injection, compared with deltoid and femoral injections. As with all insulin preparations, the time course of action of Humalog may vary considerably in different individuals or within the same individual. Patients must be educated to use proper injection techniques.

Humalog may be diluted with STERILE DILUENT for Humalog , Humulin N, Humulin 50/ 50, Humulin 70/ 30, and NPH Iletin to a concentration of 1: 10 (equivalent to U-10) or 1: 2 (equivalent to U-50). Diluted Humalog may remain in patient use for 28 days when stored at 5° C (41° F) and for 14 days when stored at 30° C (86° F). Parenteral drug products should be inspected visually prior to administration whenever the solution and the container permit. If the solution is cloudy, contains particulate matter, is thickened, or is discolored, the contents must not be injected. Humalog should not be used after its expiration date.

HOW SUPPLIED

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Humalog (insulin lispro injection, rDNA origin) vials are available in the following package size: 100 units per mL (U-100)
10 mL vials NDC 0002-7510-01 (VL-7510) Humalog (insulin lispro injection, rDNA origin) cartridges are available in the following package sizes:

5 X 1.5 mL cartridges* NDC 0002-7515-59 (VL-7515)
5 X 3 mL cartridges** NDC 0002-7516-59 (VL-7516)

Humalog (insulin lispro injection, rDNA origin) Pen, disposable insulin delivery device, is available in the following package size:
5 X 3 mL disposable insulin delivery devices NDC 0002-8725-59 (HP-8725)

* 1.5 mL cartridges are for use in Becton Dickinson and Company's B-D * Pen and Novo Nordisk A/ S's NovoPen *, NovolinPen *, and NovoPen * 1.5 insulin delivery devices.
** 3 mL cartridge is for use in Owen Mumford, Ltd. 's Autopen § 3 mL insulin delivery device. *
B-D is a registered trademark of Becton Dickinson and Company. * NovolinPen and NovoPen are registered trademarks of Novo Nordisk A/ S.

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