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Drug Description
DESCRIPTION
PREMPRO 0.3 mg/ 1.5 mg therapy consists of a single tablet containing 0. 3 mg of the conjugated estrogens (CE) found in Premarin tablets and 1.5 mg of medroxyprogesterone acetate (MPA) for oral administration. PREMPRO 0.45 mg/ 1.5 mg therapy consists of a single tablet containing 0. 45 mg of the conjugated estrogens found in Premarin tablets and 1.5 mg of medroxyprogesterone acetate for oral administration. Text Continues Below
PREMPRO 0.625 mg/ 2.5 mg therapy consists of a single tablet containing 0. 625 mg of the conjugated estrogens found in Premarin tablets and 2.5 mg of medroxyprogesterone acetate for oral administration. PREMPRO 0.625 mg/ 5 mg therapy consists of a single tablet containing 0. 625 mg of the conjugated estrogens found in Premarin tablets and 5 mg of medroxyprogesterone acetate for oral administration. PREMPHASE therapy consists of two separate tablets, a maroon Premarin tablet containing 0.625 mg of conjugated estrogens that is taken orally on days 1 through 14 and a light-blue tablet containing 0.625 mg of the conjugated estrogens found in Premarin tablets and 5 mg of medroxyprogesterone acetate that is taken orally on days 15 through 28. The conjugated equine estrogens found in Premarin tablets are a mixture of sodium estrone sulfate and sodium equilin sulfate. They contain as concomitant components, as sodium sulfate conjugates, 17 -dihydroequilin, 17 -estradiol and 17 -dihydroequilin. Medroxyprogesterone acetate is a derivative of progesterone. It is a white to off-white, odorless, crystalline powder, stable in air, melting between 200 C and 210 C. It is freely soluble in chloroform, soluble in acetone and in dioxane, sparingly soluble in alcohol and in methanol, slightly soluble in ether, and insoluble in water. The chemical name for MPA is pregn-4-ene-3, 20-dione, 17-( acetyloxy)-6-methyl-, (6 )-. Its molecular formula is C24H34O4, with a molecular weight of 386.53. Page: 1 | 2 | Next >>
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