Prempro

[Conjugated Estrogens/Medroxyprogesterone]

Patient Info
PATIENT INFORMATION

(Updated June 5, 2003)
PREMPRO (conjugated estrogens/ medroxyprogesterone acetate tablets) PREMPHASE (conjugated estrogens/ medroxyprogesterone acetate tablets)

Read this PATIENT INFORMATION before you start taking PREMPRO or PREMPHASE and read what you get each time you refill PREMPRO or PREMPHASE. There may be new information. This information does not take the place of talking to your healthcare provider about your medical condition or your treatment.

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What is the most important information I should know about PREMPRO and PREMPHASE (combinations of estrogens and a progestin)?

Do not use estrogens and progestins to prevent heart disease, heart attacks, or strokes. Using estrogens and progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots. You and your healthcare provider should talk regularly about whether you still need treatment with PREMPRO or PREMPHASE.

What is PREMPRO or PREMPHASE?

PREMPRO or PREMPHASE are medicines that contain two kinds of hormones, estrogens and a progestin.

PREMPRO or PREMPHASE is used after menopause to:

reduce moderate to severe hot flashes. Estrogens are hormones made by a woman's ovaries. The ovaries normally stop making estrogens when a woman is between 45 and 55 years old. This drop in body estrogen levels causes the "change of life" or menopause (the end of monthly menstrual periods). Sometimes, both ovaries are removed during an operation before natural menopause takes place. The sudden drop in estrogen levels causes "surgical menopause."

When the estrogen levels begin dropping, some women get very uncomfortable symptoms, such as feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating (" hot flashes" or "hot flushes"). In some women the symptoms are mild, and they will not need to take estrogens. In other women, symptoms can be more severe. You and your healthcare provider should talk regularly about whether you still need treatment with PREMPRO or PREMPHASE.

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