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Indications & Dosage
Remeron (mirtazapine) is an antidepressant, which can be given as treatment for episodes of major depression.
Each strip contains six tablet pockets, which are separated by perforations. Tear off one tablet pocket along the dotted lines.
Carefully peel off the lidding foil, starting in the corner indicated by the arrow. The tablet should be taken out of the strip with dry hands and should be placed on the tongue . The tablet will rapidly disintegrate and can be swallowed without water. Text Continues Below
Adults: The effective daily dose is usually between 15 and 45 mg; the starting dose is 15 or 30 mg (the higher dose should be taken at night). Elderly : The recommended dose is the same as that for adults. In elderly patients an increase in dosing should be done under close supervision to elicit a satisfactory and safe response. Children: Since safety and efficacy of Remeron have not been established in children, it is not recommended to treat children with Remeron. The clearance of mirtazapine may be decreased in patients with renal or hepatic insufficiency. This should be taken into account when prescribing
Remeron to this category of patients. Mirtazapine has a half-life of 20-40 hours and therefore Remeron is suitable for once-a-day administration. It should be taken preferably as a single night-time dose before going to bed. Remeron may also be given in sub-doses equally divided over the day (once in the morning and once at night-time). Treatment should preferably be continued until the patient has been completely symptom-free for 4-6 months. After this, treatment can be gradually discontinued. Treatment with an adequate dose should result in a positive response within 2-4 weeks. With an insufficient response, the dose can be increased up to the maximum dose. If there is no response within a further 2-4 weeks, then treatment should be stopped.
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