Valtrex

[Valacyclovir]

Indications & Dosage
INDICATIONS AND USAGE

Herpes Zoster

VALTREX is indicated for the treatment of herpes zoster (shingles).

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Genital Herpes

VALTREX is indicated for the treatment or suppression of genital herpes in immunocompetent individuals and for the suppression of recurrent genital herpes in HIV-infected individuals. When VALTREX is used as suppressive therapy in immunocompetent individuals with genital herpes, the risk of heterosexual transmission to susceptible partners is reduced. Safer sex practices should be used with suppressive therapy (see current Centers for Disease Control and Prevention (CDC) Sexually Transmitted Diseases Treatment Guidelines).

Cold Sores (Herpes Labialis):

VALTREX is indicated for the treatment of cold sores (herpes labialis).

DOSAGE AND ADMINISTRATION

VALTREX Caplets may be given without regard to meals.

Herpes Zoster

The recommended dosage of VALTREX for the treatment of herpes zoster is 1 gram orally 3 times daily for 7 days. Therapy should be initiated at the earliest sign or symptom of herpes zoster and is most effective when started within 48 hours of the onset of zoster rash. No data are available on efficacy of treatment started greater than 72 hours after rash
onset.

Genital Herpes

Initial Episodes

The recommended dosage of VALTREX for treatment of initial genital herpes is 1 gram twice daily for 10 days. There are no data on the effectiveness of treatment with VALTREX when initiated more than 72 hours after the onset of signs and symptoms. Therapy was most effective when administered within 48 hours of the onset of signs and symptoms. Recurrent Episodes: The recommended dosage of VALTREX for the treatment of recurrent genital herpes is 500 mg twice daily for 3 days.

If medical management of a genital herpes recurrence is indicated, patients should be advised to initiate therapy at the first sign or symptom of an episode. There are no data on the effectiveness of treatment with VALTREX when initiated more than 24 hours after the onset of signs or symptoms.

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