Bactroban Cream

[mupirocin calcium]

Drug Description
DESCRIPTION

Bactroban Cream (mupirocin calcium cream), 2% contains the dihydrate crystalline calcium hemi-salt of the antibiotic mupirocin. Chemically, it is (E, 2S, 3R, 4R, 5S)-5-[( 2S, 3S, 4S, 5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl] tetrahydro-3,4-dihydroxy- -methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid, calcium salt (2: 1), dihydrate.

The molecular formula of mupirocin calcium is (C26H43O9) 2Ca° 2H2O, and the molecular weight is 1075.3. The molecular weight of mupirocin free acid is 500.6.

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Bactroban Cream is a white cream that contains 2.15% w/ w mupirocin calcium (equivalent to 2.0% mupirocin free acid) in an oil and water-based emulsion.

The inactive ingredients are benzyl alcohol, cetomacrogol 1000, cetyl alcohol, mineral oil, phenoxyethanol, purified water, stearyl alcohol and xanthan gum.