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Ortho Evra

[NORELGESTROMIN - ETHINYL ESTRADIOL]

2. Heart attacks and strokes

Hormonal contraceptives, including ORTHO EVRAŽ, may increase the risk of developing strokes (blockage or rupture of blood vessels in the brain) and angina pectoris and heart attacks (blockage of blood vessels in the heart). Any of these conditions can cause death or serious disability. Smoking and the use of hormonal contraceptives including ORTHO EVRAŽ greatly increase the chances of developing and dying of heart disease. Smoking also greatly increases the possibility of suffering heart attacks and strokes.

3. Gallbladder disease
Women who use hormonal contraceptives, including ORTHO EVRAŽ, probably have a greater risk than nonusers of having gallbladder disease.

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4. Liver tumors
In rare cases, combination oral contraceptives can cause benign but dangerous liver tumors. Since ORTHO EVRAŽ contains hormones similar to those in birth control pills, this association may also exist with ORTHO EVRAŽ. These benign liver tumors can rupture and cause fatal internal bleeding. In addition, some studies report an increased risk of developing liver cancer. However, liver cancers are rare.

5. Cancer of the reproductive organs and breasts
Various studies give conflicting reports on the relationship between breast cancer and hormonal contraceptiveuse. Combination hormonal contraceptives, including ORTHO EVRAŽ, may slightly increase your chance of having breast cancer diagnosed, particularly after using hormonal contraceptives at a younger age. After you stop using hormonal contraceptives, the chances of having breast cancer diagnosed begin to go back down. You should have regular breast examinations by a health care professional and examine your own breasts monthly. Tell your health care professional if you have a family history of breast cancer or if you have had breast nodules or an abnormal mammogram.

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