|
Herpes zoster 1 gram every 8 hours 1 gram every 12 hours 1 gram every 24 hours 500 mg every 24 hours Genital herpes
Initial treatment 1 gram every 12 hours no reduction 1 gram every 24 hours 500 mg every 24 hours Text Continues Below
Genital herpes
Recurrent episodes
500 mg every 12 hours no reduction 500 mg every 24 hours 500 mg every 24 hours Genital herpes
Suppressive therapy
1 gram every 24 hours no reduction 500 mg every 24 hours 500 mg every 24 hours 500 mg every 24 hours no reduction 500 mg every 48 hours 500 mg every 48 hours Genital herpes
Suppressive therapy in HIV-infected patients
500 mg every 12 hours no reduction 500 mg every 24 hours 500 mg every 24 hours Herpes labialis (cold sores)
Do not exceed 1 day of treatment.
Two 2-gram doses taken about 12 hours apart Two 1-gram doses taken about 12 hours apart Two 500-mg doses taken about 12 hours apart 500-mg
single dose Hemodialysis During hemodialysis, the half-life of acyclovir after administration of VALTREX is approximately 4 hours. About one third of acyclovir in the body is removed by dialysis during a 4-hour hemodialysis session. Patients requiring hemodialysis should receive the recommended dose of VALTREX after hemodialysis. Peritoneal Dialysis There is no information specific to administration of VALTREX in patients receiving peritoneal dialysis. The effect of chronic ambulatory peritoneal dialysis (CAPD) and continuous arteriovenous hemofiltration/dialysis (CAVHD) on acyclovir pharmacokinetics has been studied. The removal of acyclovir after CAPD and CAVHD is less pronounced than with hemodialysis, and the pharmacokinetic parameters closely resemble those observed in patients with ESRD not receiving hemodialysis. Therefore, supplemental doses of VALTREX should not be required following CAPD or CAVHD. HOW SUPPLIED VALTREX Caplets (blue, film-coated, capsule-shaped tablets) containing valacyclovir hydrochloride equivalent to 500 mg valacyclovir and printed with "VALTREX 500 mg." Bottle of 30 (NDC 0173-0933-08) and unit dose pack of 100 (NDC 0173-0933-56). VALTREX Caplets (blue, film-coated, capsule-shaped tablets) containing valacyclovir hydrochloride equivalent to 1 gram valacyclovir and printed with "VALTREX 1 gram." Bottle of 21 (NDC 0173-0565-02). Store at 15° to 25°C (59° to 77°F). GlaxoSmithKline
Research Triangle Park, NC 27709 ©2003, GlaxoSmithKline. All rights reserved.
August 2003 RL-2037 Page: << Prev | 1 | 2 | 3
|
.gif)
