|
Treatment Following Acute Myocardial Infarction Treatment of hemodynamically stable patients may be started as early as within 24 hours following the onset of symptoms of myocardial infarction. Patients should receive, as appropriate, standard recommended treatments (see INDICATIONS AND CLINICAL USE, Treatment Following Acute Myocardial Infarction). The first dose of PRINIVIL ® is 5 mg given orally, followed by 5 mg after 24 hours, 10 mg after 48 hours and then 10 mg once daily thereafter. Patients with a low systolic blood pressure (between 100 and 120 mmHg) when treatment is started or during the first three days after the infarct should be given a lower dose, 2.5 mg orally (Treatment with PRINIVIL ® must not be initiated in patients who are at risk of serious hemodynamic deterioration (see PRECAUTIONS, Hypotension Following Acute Myocardial Infarction). Text Continues Below
After three days if hypotension occurs (systolic blood pressure less than or equal to 100 mmHg), a daily maintenance dose of 5 mg may be given with temporary reductions to 2.5 mg if needed. If prolonged hypotension occurs (systolic blood pressure less than 90 mmHg for more than one hour), PRINIVIL ® should be withdrawn. Renal function should be assessed before and during therapy with PRINIVIL ® (see PRECAUTIONS, Renal Impairment). Dosing should normally continue for six weeks. At that time, patients with signs or symptoms of heart failure should continue with PRINIVIL ® (see DOSAGE AND ADMINISTRATION, Congestive Heart Failure). PRINIVIL ® is compatible with intravenous or transdermal glyceryl trinitrate. Page: << Prev | 1 | 2 | 3 | 4 | 5
|
.gif)
