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(Ivanhoe Newswire) Good blood could run in your blood! New research shows high levels of HDL cholesterol (HDL-C), also known as good cholesterol, could arise from a genetic mutation.
Researchers found mutations in the LIPG gene, which codes for the endothelial lipase enzyme, result in high plasma HDL-C levels. Individuals with high plasma HDL-C levels are at a decreased risk of developing coronary artery disease a condition where plaque builds up inside the coronary arteries, putting the patient at an increased risk of heart attack.
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Based on this data, researchers report inhibition of endothelial lipase is likely to raise HDL-C levels in humans. However, further research will need to be conducted to determine if the rise in HDL-C levels could impact cardiovascular health.
SOURCE: The Journal of Clinical Investigation, 2009
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