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(Ivanhoe Newswire) Following results of a new study, researchers question the efficacy of the antidepressant, citalopram, for the treatment of repetitive behaviors in children with autism.
Citalopram is in a class of antidepressants know as selective serotonin reuptake inhibitors (SSRIs), designed to interfere with the way the brain regulates serotonin.
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"Despite the relative dearth of evidence supporting their use, SSRIs are among the most frequently used medications for children with autism, partially because of their perceived safety," the study authors write.
However, new research shows citalopram was associated with adverse events, including increased energy level, impulsiveness, decreased concentration, hyperactivity, diarrhea, insomnia and stereotypy, the mechanical repetition of the same posture or movement.
"There is growing recognition that children and adolescents with autism spectrum disorders have serious behavioral problems and psychiatric symptoms that may be appropriate targets for pharmacotherapy," the authors write. "The results of this trial indicate that citalopram is not an effective treatment for children having autism spectrum disorders with moderate or greater repetitive behavior."
SOURCE: The Archives of General Psychiatry, 2009;66[6]:583-590
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